CHEM 3321: Laboratory for Organic Chemistry I
This lab course is for biochemistry and non-chemistry majors. A large part of Chem 3321 is spent learning techniques in organic chemistry, including TLC, distillation, extraction, crystallization, and IR spectroscopy. Once these techniques are mastered, they are employed in the final four labs of the semester. Two laboratory periods are devoted to working with molecular models sets to study nomenclature, conformational analysis, and stereochemistry.
- 3321 Course Syllabus, Schedule and Policies
- Traffic flow patterns for Ekeley M1B floor
- Drawer check-in sheet and glassware prices
- Example lab report
TA office hours and emails are posted here.
| Lab | Day | Time | Location | TA | TA Email |
| 113/114 | M | 1:50 PM-4:40 PM | EKLC M1B65 | Brendan Langmack | Brendan.Langmack@colorado.edu |
| 115 | M | 5:30 PM-8:20 PM | remote | Brendan Langmack | Brendan.Langmack@colorado.edu |
| 121/122 | T | 10:20 AM-1:10 PM | EKLC M1B65 | Brendan Langmack | Brendan.Langmack@colorado.edu |
| 123/124 | T | 1:50 PM-4:40 PM | EKLC M1B65 | Madeline Walden | Madeline.Walden@colorado.edu |
| 131/132 | W | 10:20 AM-1:10 PM | EKLC M1B65 | Madeline Walden | Madeline.Walden@colorado.edu |
| 133/134 | W | 1:50 PM-4:40 PM | EKLC M1B65 | Hoai Pham | Hoai.Pham@colorado.edu |
| 135 | W | 5:30 PM-8:20 PM | remote | Hoai Pham | Hoai.Pham@colorado.edu |
| 136 | W | 5:30 PM-8:20 PM | remote | Phuc Pham | Phuc.Pham@colorado.edu |
| 141/142 | R | 10:20 AM-1:10 PM | EKLC M1B65 | Scott Brody | Scott.Brody@colorado.edu |
| 143/144 | R | 1:50 PM-4:40 PM | EKLC M1B65 | Madeline Walden | Madeline.Walden@colorado.edu |
| 145 | R | 5:30 PM-8:20 PM | remote | Yiming Hu | Yiming.Hu@colorado.edu |
| 146 | R | 5:30 PM-8:20 PM | remote | Phuc Pham | Phuc.Pham@colorado.edu |
| 151 | F | 10:20 AM-1:10 PM | remote | Yiming Hu | Yiming.Hu@colorado.edu |
| 152 | F | 10:20 AM-1:10 PM | remote | Yiming Hu | Yiming.Hu@colorado.edu |
| 153 | F | 1:50 PM-4:40 PM | remote | Justin Olson | Justin.Olson-1@colorado.edu |
| 154 | F | 1:50 PM-4:40 PM | remote | Phuc Pham | Phuc.Pham@colorado.edu |
Experiment Schedule
To find which experiment you will perform each week, look up your section and the week in the first table below, then check this number against the second table below. “n/a” means your lab section will not meet during that week.
| Week | 113 115 | 114 | 121 123 | 122 124 | 131 133 135 | 132 134 136 | 141 143 145 | 142 144 146 | 151 153 | 152 154 |
| Mon Jan 11 - Fri Jan 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
| Mon Jan 18 - Fri Jan 22 | n/a | n/a | n/a | n/a | 1 | 1 | 1 | 1 | 1 | 1 |
| Mon Jan 25 - Fri Jan 29 | 1 | 1 | 1 | 1 | 2 | n/a | 2 | n/a | 2 | n/a |
| Mon Feb 1 - Fri Feb 5 | 2 | n/a | 2 | n/a | 3 | 2 | 3 | 2 | 3 | 2 |
| Mon Feb 8 - Fri Feb 12 | 3 | 2 | 3 | 2 | 4 | 3 | 4 | 3 | 4 | 3 |
| Mon Feb 15 - Fri Feb 19 | 4 | 3 | 4 | 3 | n/a | n/a | 5 | 4 | 5 | 4 |
| Mon Feb 22 - Fri Feb 26 | 5 | 4 | 5 | 4 | 5 | 4 | 6 | 5 | 6 | 5 |
| Mon Mar 1 - Fri Mar 5 | 6 | 5 | 6 | 5 | 6 | 5 | 7 | 6 | 7 | 6 |
| Mon Mar 8 - Fri Mar 12 | 7 | 6 | 7 | 6 | 7 | 6 | 8 | 7 | 8 | 7 |
| Mon Mar 15 - Fri Mar 19 | 8 | 7 | 8 | 7 | 8 | 7 | 9 | 8 | 9 | 8 |
| Mon Mar 22 - Fri Mar 26 | 9 | 8 | 9 | 8 | 9 | 8 | n/a | n/a | 10 | 9 |
| Mon Mar 29 - Fri Apr 2 | 10 | 9 | 10 | 9 | 10 | 9 | 10 | 9 | 11 | 10 |
| Mon Apr 5 - Fri Apr 9 | 11 | 10 | 11 | 10 | 11 | 10 | 11 | 10 | 12 | 11 |
| Mon Apr 12 - Fri Apr 16 | 12 | 11 | 12 | 11 | 12 | 11 | 12 | 11 | F | 12 |
| Mon Apr 19 - Fri Apr 23 | F | 12 | F | 12 | F | 12 | F | 12 | n/a | F |
| Mon Apr 26 - Fri Apr 30 | n/a | F | n/a | F | n/a | F | n/a | F | n/a | n/a |
Experiment Schedule
Due to COVID, each lab section will be split into two groups, and only one group will perform an in-person experiment each week while the other group performs a remote experiment.
| # | Experiment | Quiz | Notes |
| 1 | REMOTE Syllabus, COVID Safety, Lab Safety & IR Spectroscopy |
Yes (safety quiz) | Experiment 1 and the Handbook chapters on Lab Safety and IR are available as PDFs in Canvas. This Lab Safety Movie and IR Tutorial may also help. |
| 2 | REMOTE Modeling Conformations, ChemDraw & Excel |
No | You can save time by downloading and installing ChemDraw ahead of time. |
| 3 | REMOTE Labster I |
No | You will perform some virtual experiments in Labster this week. Details TBD. |
| 4 | IN-PERSON/REMOTE NMR Spectroscopy (In-person if your section performs this experiment after campus reopens) |
No | Chapter 18 & Chapter 20 in the Lab Handbook and Chapter 13 in Loudon;
Spectroscopy Tutorial and
NMR Theory Tutorial on this web site. The in-class Spectroscopy Worksheet (in the experiment manual) is due before you leave today. The Spectroscopy Homework is due later. Download this file and print the pages you are assigned. |
| 5 | REMOTE Labster II |
Yes (NMR Quiz due) | You will perform some virtual experiments in Labster this week. Details TBD. |
| 6 | IN-PERSON Practical NMR |
No | You will need to download and install MestreNova, and get the NMR data files for this lab. |
| 7 | REMOTE Modelling Chirality & Cycloalkanes |
No | You can check out a model set if you don't have one. |
| 8 | IN-PERSON Thin Layer Chromatography and Melting Point |
Yes (SQ Answers) | This is the first experiment this term that has a full lab report associated with it. The Handbook contains a chapter on writing lab reports. Be sure to write up a prelab and submit it in Canvas by the start of lab!
TLC procedure and more Melting points Melting point movie (10:45 into the Crystallization movie) During this experiment, you will also submit samples for your Practical NMR lab, so you can work up the spectra next week. |
| 9 | REMOTE Labster IIi |
No | You will perform some virtual experiments in Labster this week. Details TBD. |
| 10 | IN-PERSON Extraction |
Yes (SQ Answers) | Extraction procedure Extraction movie Remember to save the product from this lab for the next lab. |
| 11 | REMOTE Stereochemistry of Alkene Additions |
No | Instead of a prelab quiz, fill in the worksheet included with the lab. Since this experiment is remote, you'll watch a video of your TA performing the experiment and write a lab report based on their data. |
| 12 | IN-PERSON Regiochemistry of Eliminations & Lab Check-out |
Yes (SQ Answers) | You can download the NMR spectrum for 3-methylcyclohexene. |
| F | REMOTE Final Quiz |
Yes | For the final quiz, you should review the study questions, worksheets and prelab quizzes. |
