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CHEM 3321: Laboratory for Organic Chemistry I

This lab course is for biochemistry and non-chemistry majors. A large part of Chem 3321 is spent learning techniques in organic chemistry, including TLC, distillation, extraction, crystallization, and IR spectroscopy. Once these techniques are mastered, they are employed in the final four labs of the semester. Two laboratory periods are devoted to working with molecular models sets to study nomenclature, conformational analysis, and stereochemistry.

TA office hours and emails are posted here.

101/801T10:20 AM-1:10 PMEKLC M1B20Brandon Bishop
102T10:20 AM-1:10 PMEKLC M1B65Claire Boronski
111T1:50 PM-4:40 PMEKLC M1B20Shea OSullivan
112T1:50 PM-4:40 PMEKLC M1B65Madeline Walden
121W10:20 AM-1:10 PMEKLC M1B20Kamil Marsalek
122W10:20 AM-1:10 PMEKLC M1B65Tessa Myren
123W10:20 AM-1:10 PMremoteMicah Ohlhausen
131W1:50 PM-4:40 PMEKLC M1B20Keira Culley
132W1:50 PM-4:40 PMEKLC M1B65Hoai Pham
133W1:50 PM-4:40 PMremotePhuc Pham
141W5:30 PM-8:20 PMEKLC M1B20Scott Brody
142W5:30 PM-8:20 PMEKLC M1B65Madeline Walden
143W5:30 PM-8:20 PMremoteRuiheng Jing
151R10:20 AM-1:10 PMEKLC M1B20Brendan Langmack
152R10:20 AM-1:10 PMEKLC M1B65Claire Boronski
161R1:50 PM-4:40 PMEKLC M1B20Brandon Bishop
162R1:50 PM-4:40 PMEKLC M1B65Brendan Langmack
171R5:30 PM-8:20 PMEKLC M1B20Scott Brody
172R5:30 PM-8:20 PMEKLC M1B65Madeline Walden
173R5:30 PM-8:20 PMremoteRuiheng Jing
181F10:20 AM-1:10 PMEKLC M1B20Garrett Evenson
182F10:20 AM-1:10 PMEKLC M1B65Tessa Myren
191F1:50 PM-4:40 PMEKLC M1B20Keira Culley
192F1:50 PM-4:40 PMEKLC M1B65Hoai Pham
194M10:20 AM-1:10 PMEKLC M1B20Zepeng Lei
195M10:20 AM-1:10 PMEKLC M1B65Tessa Myren
196M1:50 PM-4:40 PMremoteRachel Weintraub
197M1:50 PM-4:40 PMremotePhuc Pham
198M5:30 PM-8:20 PMremoteRuiheng Jing
199M5:30 PM-8:20 PMremotePhuc Pham

Experiment Schedule

Due to COVID, each lab section will be split into two groups, and only one group will perform an in-person experiment each week while the other group performs a remote experiment.

Dates for Group 1 Dates for Group 2 Experiment Quiz Notes
Aug 24 - Aug 28 Aug 24 - Aug 28 REMOTE
Syllabus & COVID safety
n/a Aug 31 - Sep 4 No labs Group 2 won't meet during the second week of the semester.
Aug 31 - Sep 4 Sep 7 - Sep 11 IN PERSON
Lab Check-in & Exp. 1: Lab Safety & IR Spectroscopy
No During the week of Labor Day, all Monday students will have to perform this experiment remotely.
Be sure to read the safety chapter in the handbook before lab and wear proper lab attire. Experiment 1 and the Handbook chapters on Lab Safety and IR are available as PDFs in Canvas. This Lab Safety Movie and IR Tutorial may also help.
Sep 7 - Sep 11 Sep 14 - Sep 18 REMOTE
Exp. 2: NMR Spectroscopy
Yes (safety quiz) Chapter 18 & Chapter 20 in the Lab Handbook and Chapter 13 in Loudon; Spectroscopy Tutorial and NMR Theory Tutorial on this web site.
The in-class Spectroscopy Worksheet (in the experiment manual) is due before you leave today. The Spectroscopy Homework is due later. Download this file and print the pages you are assigned.
Sep 14 - Sep 18 Sep 21 - Sep 25 IN PERSON
Exp. 3: Modeling Conformations, ChemDraw & Excel
Yes (NMR quiz) You can check out a model set if you don't have one. You can also save time by downloading and installing ChemDraw ahead of time.
Since Sep. 7 is Labor Day, Group 1 students in Monday labs will have to perform this experiment remotely.
Sep 21 - Sep 25 Sep 28 - Oct 2 REMOTE
Exp. 4: Labster I
No You will perform some virtual experiments in Labster this week. Details TBD.
Sep 28 - Oct 2 Oct 5 - Oct 9 IN PERSON
Exp. 5: Thin Layer Chromatography and Melting Point
Yes (SQ Answers) This is the first experiment this term that has a full lab report associated with it. The Handbook contains a chapter on writing lab reports. Be sure to write up a prelab and submit it in Canvas by the start of lab! TLC procedure and more
Melting points
Melting point movie (10:45 into the Crystallization movie)
During this experiment, you will also submit samples for your Practical NMR lab, so you can work up the spectra next week.
Oct 5 - Oct 9 Oct 12 - Oct 16 REMOTE
Exp. 6: Practical NMR
No You will need to download and install MestreNova, and get the NMR data files for this lab.
Oct 12 - Oct 16 Oct 19 - Oct 23 IN PERSON
Exp. 7: Extraction
Yes (SQ Answers) Extraction procedure
Extraction movie
Remember to save the product from this lab for the next lab.
Oct 19 - Oct 23 Oct 26 - Oct 30 REMOTE
Exp. 8: Modelling Chirality & Cycloalkanes
No You can check out a model set if you don't have one.
Oct 26 - Oct 30 Nov 2 - Nov 6 IN PERSON
Exp. 9: Recrystallization
Yes (SQ Answers) Recrystallization movie
Recrystallization procedure
Nov 2 - Nov 6 Nov 9 - Nov 13 REMOTE
Exp. 10: Labster II
No You will perform some virtual experiments in Labster this week. Details TBD.
Nov 9 - Nov 13 Nov 16 - Nov 20 IN PERSON
Exp. 11: Stereochemistry of Alkene Additions & Lab Check-out
No Instead of a prelab quiz, fill in the worksheet included with the lab.
If you have the 11th edition of the handbook, you will need the Handbook supplement on Green Chemistry.
Nov 16 - Nov 20 Nov 30 - Dec 4 REMOTE
Exp. 12: Labster III
No You will perform some virtual experiments in Labster this week. Details TBD.
Nov 30 - Dec 4 Nov 30 - Dec 4 REMOTE
Final Quiz
Yes For the final quiz, you should review the study questions, worksheets and prelab quizzes.