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CHEM 3321: Laboratory for Organic Chemistry I

This lab course is for biochemistry and non-chemistry majors. A large part of Chem 3321 is spent learning techniques in organic chemistry, including TLC, distillation, extraction, crystallization, and IR spectroscopy. Once these techniques are mastered, they are employed in the final four labs of the semester. Two laboratory periods are devoted to working with molecular models sets to study nomenclature, conformational analysis, and stereochemistry.

TA office hours and emails are posted here.

LabDayTimeLocationTATA Email
113/114M1:50 PM-4:40 PMEKLC M1B65Brendan LangmackBrendan.Langmack@colorado.edu
115M5:30 PM-8:20 PMremoteBrendan LangmackBrendan.Langmack@colorado.edu
121/122T10:20 AM-1:10 PMEKLC M1B65Brendan LangmackBrendan.Langmack@colorado.edu
123/124T1:50 PM-4:40 PMEKLC M1B65Madeline WaldenMadeline.Walden@colorado.edu
131/132W10:20 AM-1:10 PMEKLC M1B65Madeline WaldenMadeline.Walden@colorado.edu
133/134W1:50 PM-4:40 PMEKLC M1B65Hoai PhamHoai.Pham@colorado.edu
135W5:30 PM-8:20 PMremoteHoai PhamHoai.Pham@colorado.edu
136W5:30 PM-8:20 PMremotePhuc PhamPhuc.Pham@colorado.edu
141/142R10:20 AM-1:10 PMEKLC M1B65Scott BrodyScott.Brody@colorado.edu
143/144R1:50 PM-4:40 PMEKLC M1B65Madeline WaldenMadeline.Walden@colorado.edu
145R5:30 PM-8:20 PMremoteYiming HuYiming.Hu@colorado.edu
146R5:30 PM-8:20 PMremotePhuc PhamPhuc.Pham@colorado.edu
151F10:20 AM-1:10 PMremoteYiming HuYiming.Hu@colorado.edu
152F10:20 AM-1:10 PMremoteYiming HuYiming.Hu@colorado.edu
153F1:50 PM-4:40 PMremoteJustin OlsonJustin.Olson-1@colorado.edu
154F1:50 PM-4:40 PMremotePhuc PhamPhuc.Pham@colorado.edu

Experiment Schedule

To find which experiment you will perform each week, look up your section and the week in the first table below, then check this number against the second table below. “n/a” means your lab section will not meet during that week.

Week113
115
114121
123
122
124
131
133
135
132
134
136
141
143
145
142
144
146
151
153
152
154
Mon Jan 11 - Fri Jan 15n/an/an/an/an/an/an/an/an/an/a
Mon Jan 18 - Fri Jan 22n/an/an/an/a111111
Mon Jan 25 - Fri Jan 2911112n/a2n/a2n/a
Mon Feb 1 - Fri Feb 52n/a2n/a323232
Mon Feb 8 - Fri Feb 123232434343
Mon Feb 15 - Fri Feb 194343n/an/a5454
Mon Feb 22 - Fri Feb 265454546565
Mon Mar 1 - Fri Mar 56565657676
Mon Mar 8 - Fri Mar 127676768787
Mon Mar 15 - Fri Mar 198787879898
Mon Mar 22 - Fri Mar 26989898n/an/a109
Mon Mar 29 - Fri Apr 21091091091091110
Mon Apr 5 - Fri Apr 911101110111011101211
Mon Apr 12 - Fri Apr 161211121112111211F12
Mon Apr 19 - Fri Apr 23F12F12F12F12n/aF
Mon Apr 26 - Fri Apr 30n/aFn/aFn/aFn/aFn/an/a

Experiment Schedule

Due to COVID, each lab section will be split into two groups, and only one group will perform an in-person experiment each week while the other group performs a remote experiment.

# Experiment Quiz Notes
1 REMOTE
Syllabus, COVID Safety, Lab Safety & IR Spectroscopy
Yes (safety quiz) Experiment 1 and the Handbook chapters on Lab Safety and IR are available as PDFs in Canvas. This Lab Safety Movie and IR Tutorial may also help.
2 REMOTE
Modeling Conformations, ChemDraw & Excel
No You can save time by downloading and installing ChemDraw ahead of time.
3 REMOTE
Labster I
No You will perform some virtual experiments in Labster this week. Details TBD.
4 IN-PERSON/REMOTE
NMR Spectroscopy (In-person if your section performs this experiment after campus reopens)
No Chapter 18 & Chapter 20 in the Lab Handbook and Chapter 13 in Loudon; Spectroscopy Tutorial and NMR Theory Tutorial on this web site.
The in-class Spectroscopy Worksheet (in the experiment manual) is due before you leave today. The Spectroscopy Homework is due later. Download this file and print the pages you are assigned.
5 REMOTE
Labster II
Yes (NMR Quiz due) You will perform some virtual experiments in Labster this week. Details TBD.
6 IN-PERSON
Practical NMR
No You will need to download and install MestreNova, and get the NMR data files for this lab.
7 REMOTE
Modelling Chirality & Cycloalkanes
No You can check out a model set if you don't have one.
8 IN-PERSON
Thin Layer Chromatography and Melting Point
Yes (SQ Answers) This is the first experiment this term that has a full lab report associated with it. The Handbook contains a chapter on writing lab reports. Be sure to write up a prelab and submit it in Canvas by the start of lab! TLC procedure and more
Melting points
Melting point movie (10:45 into the Crystallization movie)
During this experiment, you will also submit samples for your Practical NMR lab, so you can work up the spectra next week.
9 REMOTE
Labster IIi
No You will perform some virtual experiments in Labster this week. Details TBD.
10 IN-PERSON
Extraction
Yes (SQ Answers) Extraction procedure
Extraction movie
Remember to save the product from this lab for the next lab.
11 REMOTE
Stereochemistry of Alkene Additions
No Instead of a prelab quiz, fill in the worksheet included with the lab. Since this experiment is remote, you'll watch a video of your TA performing the experiment and write a lab report based on their data.
12 IN-PERSON
Regiochemistry of Eliminations & Lab Check-out
Yes (SQ Answers) You can download the NMR spectrum for 3-methylcyclohexene.
F REMOTE
Final Quiz
Yes For the final quiz, you should review the study questions, worksheets and prelab quizzes.